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Concentration-effect curves to increasing concentrations of PPT (A), 17-β estradiol (E2) (B), Provinols™ (C) or delphinidin (D) in aortic rings, with functional endothelium precontracted with U46619, taken from ERα Wild Type (open circles) and Knock-Out (filled circles) mice (n = 5–6). **P<0.01, ***P<0.001.
