Table 5. Correlations between β2*-nAChR Availability and Baseline Assessments.
| Smoker 1 day (n=7) | Smoker 1 week (n=10)** | Smoker 2 weeks (n=7)† | Smoker 4 weeks (n=11) | Smoker 6-12 weeks (n=6)† | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Region | MNWS | QSU Intent | QSU Relief | MNWS | QSU Intent | QSU Relief | MNWS | QSU Intent | QSU Relief | MNWS | QSU Intent | QSU Relief | MNWS | QSU Intent | QSU Relief |
| Thalamus | .16 | -.90* | -.56 | .06 | .29 | .17 | -.31 | - | - | .22 | -.34 | -.05 | .83 | - | - |
| Striatum | -.05 | -.76 | -.56 | -.01 | .16 | .17 | -.31 | - | - | .17 | -.29 | -.29 | .43 | - | - |
| Parietal Cortex | .27 | -.88* | -.56 | -.15 | .45 | -.20 | .02 | - | - | -.03 | -.49 | -.67 | .66 | - | - |
| Frontal Cortex | .09 | -.78 | -.49 | .06 | -.31 | -.18 | -.31 | - | - | .08 | -.53 | -.43 | .89 | - | - |
| Anterior Cingulate | -.22 | -.63 | -.51 | .02 | .46 | .18 | -.20 | - | - | .17 | -.35 | -.39 | .77 | - | - |
| Temporal Cortex | -.34 | -.67 | -.63 | .07 | .46 | .23 | -.34 | - | - | .25 | -.37 | -.25 | .89 | - | - |
| Occipital Cortex | -.11 | -.67 | -.32 | .22 | .12 | .59 | -.45 | - | - | .48 | -.73 | .05 | .89 | - | - |
| Cerebellum | -.02 | -.85 | -.52 | .11 | -.09 | .12 | -.34 | - | - | .64 | -.61 | .21 | .77 | - | - |
*
p≤0.01 (two-tailed)
**
Due to missing QSU baseline data, correlations were only conducted in 10 of 17 subjects.
†
Due to missing QSU baseline data, Spearman's correlations could not be conducted.