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. Author manuscript; available in PMC: 2009 Dec 22.
Published in final edited form as: Am J Transplant. 2008 Jun;8(6):1214–1220. doi: 10.1111/j.1600-6143.2008.02248.x

Figure 3. High frequency of HCV-specific IL-10 producing T lymphocytes in OLT recipients with HCV-induced allograft cirrhosis.

Figure 3

The frequency of peripheral blood T lymphocytes specific to HCV derived proteins, NS3, NS4, NS5 and core was determined by means of IL-10 ELISPOT assay. The data is representative of all experiments done in triplicate and the standard error bars are demonstrated. Patients with hepatic fibrosis (HFC, n=25, black bars) demonstrated significantly higher frequency of IL-10 producing HCV-specific T lymphocytes compared to patients with hepatic inflammation (HIN, n=49, white bars) and healthy control individuals (n=20, grey bars, p<0.05). The frequency of T lymphocytes reactive to the mumps antigen was comparable.