Table 1.
HIN* (n=49) | HFC* (n=25) | p value | |
---|---|---|---|
Age | 51.7 ± 6.77 | 52.5 ± 5.98 | 0.9 |
Gender (M:F) | 26 : 23 | 13 : 12 | 0.7 |
Fibrosis stage | 0–2 | 3–4 | |
HCV genotype | α | β | |
1 | 29 | 14 | |
Non-1 | 6 | 4 | |
HCV load (log IU/ml) | |||
Pre-Transplant | 13.57 ± 12.46 | 13.67 ± 12.27 | 0.7 |
HCV load (IU/ml) | |||
Post-transplant | 15.78 ± 13.68 | 15.75 ± 13.42 | 0.7 |
Pre-transplant CTP Score | |||
5–6 | 10 | 6 | |
7–9 | 28 | 12 | |
10–15 | 11 | 7 | 0.6 |
CMV Status | γ | δ | |
D+R− | 7 (14.3%) | 4 (16%) | |
D−R+ | 7 (14.3%) | 3 (12%) | 0.7 |
D+R+ | 21 (42.9%) | 8 (32%) | |
D−R− | 6 (12.2%) | 5 (20%) | |
Coexistent Alcohol | 17 | 10 | 0.8 |
Immunosuppression | |||
Tacrolimus | 16 (64%) | 0.48 | |
Cyclosporine | 32 (65.3%) | 7 (24%) | |
Sirolimus | 8 (16.3%) | 3 (12%) | |
MMF | 9 (18.4%) | 12 (48%) | 0.9 |
Myfortic | 16 (32.7%) | 2 (8%) | |
AZA | 2 (4.1%) | 0 | |
Prednisone | 0 | 5 (20%) | |
12 (24.5%) | |||
No. acute rejection | 15 (30.1%) | 9 (36%) | 0.9 |
Mean cumulative solumedrol (gms) |
0.18 | 0.15 | 0.8 |
HIN= Hepatic Inflammation, HFC= Hepatic Fibrosis/ cirrhosis, D=Donor, R=Recipient
α, β, γ, δ not available in 14, 7, 8, and 5 cases, respectively.