Figure 3.

Comparison of transcript levels of catalase (Cat), superoxide dismutase 1 and 2 (Sod1 and Sod2, respectively), and glutathione transferases 1 plus 2 (Gsta1+2) in livers of C57BL/6 and 129/sv mouse strains. Transcript levels were determined by reverse transcription real-time polymerase chain reaction. The bars represent ratios (± SD of the ratio) of mean transcript levels (normalized to the level of ribosomal protein S3 [Rps3] transcript) of three animals per group. Statistically significant differences between the C57BL/6 and 129/sv strains (i.e., transcript ratios of C57BL/6 vs 129/sv animals differing from 1; p < .05 by t test) are indicated by asterisks. The comparison was carried out separately for wild-type (filled bars) and for mGsta4-null (open bars) mice in the C57BL/6 and 129/sv genetic backgrounds.