Figure 2.

Inheritance of methylation patterns in pedigrees of transgenic mouse lines containing deletion derivatives of the HRD transgene. Filled symbols indicate methylated transgene arrays, open symbols indicate unmethylated arrays, and partially filled symbols indicate partially methylated transgenes. The partially methylated transgenes seen in the ΔG pedigrees were in general substantially more methylated than those in other lines (see Fig. 3). The Ssm1 genotype is indicated by lowercase letters (b, d, or s). Those mice used for the analysis presented in Fig. 3 are marked with genotype designations or with asterisks. (A) Two HRDΔP lines. (B) Two HRDΔE lines. (C) Two HRDΔG lines. (D) A gpt-only line.