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. 2010 Jan 1;137(1):53–61. doi: 10.1242/dev.041749

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Fig. 4. — Effects of Notch manipulation on monotypic lineages. Examples of MARCM clones for lineages that are monotypic (A,B) or produce a major and minor class of neuron (C,D). Green, anti-CD8; magenta, anti-neurotactin. Insets are a reduced grayscale image of each clone, except for F, which shows the neurotactin channel. (A-D) Wild-type NB clones. (E-H) NB clones that are homozygous Notch null. (E) A lineage 0 clone with the neuroblast (N) associated with a compact cell cluster containing a neurite bundle that dwindles as it enters the neuropil. (F) A lineage 2 clone consisting of the NB and a few associated cells but no emerging neurites. The neurotactin-positive bundle of its wild-type, contralateral homolog is indicated by the yellow arrowhead; this bundle is missing on the side with the clone. (G,H) NB clones showing just the rare cell-type and a slightly separated NB with a small compact ball of associated cells. (I-L) NB clones that express Notch^CA. Neurite bundle names are as in Fig. 2.