Table 3.

AhR relative gene expression, by family history of upper gastrointestinal tract (UGI) cancer, dysplasia, and indoor air pollution exposure status

Category	Number of Subjects	Fold Change in AhR Gene Expression [Median relative gene expression (IQR)]*
Without a Family History of UGI Cancer (reference)	83	1.0 [-18000 (-18000, -1036)]
With a Family History of UGI Cancer	64	9.2 [-1964 (-18000, -610)]
Without Esophageal Dysplasia (reference)	97	1.0 [-2434 (-18000, -711)]
With High Grade Esophageal Dysplasia	50	0.1 [-18000 (-18000, -847)]
Indoor Air Pollution With Low Exposure (reference)	76	1.0 [-3714 (-18000, -1010)]
With High Exposure	71	1.2 [-3015 (-18000, -623)]
Non Smoker (reference)	99	1.0 [-4904 (-18000, -623)]
Smoker	48	2.0 [-2386 (-18000, -1026)]
Male (reference)	74	1.0 [-3906 (-18000, -1351)]
Female	73	1.4 [-2668 (-18000, -533)]

^*Log2 ΔΔCT sample value

Wilcoxon rank-sum and linear regression tests: Family History of Cancer p=0.02, p=0.02; Esophageal Dysplasia p=0.3, p=0.1; Indoor air pollution p=0.6, p=0.6; Smoking status p=0.4, p=0.4; Gender p=0.04., p=0.2.