Fig. 3.

IFN-γ-producing cells in PBMCs from SARS-recovered individuals in response to S, M, E and N peptides. a Representative images of IFN-γ ELISPOT results from five donors, patients 1, 2, 5, 12 and 20. b Mean spot numbers in PBMCs from 21 SARS-recovered donors and 7 healthy control donors in response to S, M, E and N peptides. The number of spots in the medium controls ranged from 0 to 2. All assays were performed in triplicate. Bars indicate mean values. *P < 0.05, **P < 0.01, NS: P > 0.05. # P2 in response to S, M and N; △P15 in response to S and N. c Percentage of donors responding to S, M, E and N peptides. ++++ percentage of donors responding to all four of S, M, E and N peptides; +++ percentage of donors responding to three of S, M, E and N peptides; ++ percentage of donors responding to two of S, M, E and N peptides; + percentage of donors responding to one of S, M, E and N peptides; − percentage of donors responding to none of S, M, E and N peptides