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SPR images of an oligonucleotide array synthesized on a carbon-on-silver substrate. (a) Computer-generated image of the array. (b) SPR reference image of the array. (c) SPR image of the array after hybridization with Complement 1. This is a difference image, which is the image after hybridization of Complement 1 minus the reference image. (d) Difference image of the array after the hybridization of Complement 2 (minus figure 9c).
