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. 2009 Sep 16;284(46):31776–31788. doi: 10.1074/jbc.M109.047928

FIGURE 2.

FIGURE 2.

Structure of the plakoglobin arm domain and C-terminal helix bound to phosphorylated E-cadherin. A, overall structure of the plakoglobin-pE-CBD complex. Plakoglobin arm repeat helices are shown in yellow (H1 and H2) and blue (H3), and helix C is shown in red. The pE-CBD is shown in magenta. B, superposition of the plakoglobin arm domain (yellow H1 and H2 and blue H3) with the β-catenin arm domain (gray) as seen in the β-cat-arm-pEcyto complex (33). The orientation is that same as in A. H1 and H2 helices are shown in gray and H3 in blue. The pEcyto structure is shown in cyan. C, superposition of the pE-cadherin CBD bound to plakoglobin (magenta) and β-catenin (cyan). The arm repeat domains of β-catenin and plakoglobin were superimposed, and the transformation was used to compare the bound cadherins.