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. 2009 Sep 23;284(46):31882–31892. doi: 10.1074/jbc.M109.014522

FIGURE 6.

FIGURE 6.

Schematic of the reactions catalyzed by BacA and BacB. Prephenate is converted into an unstable intermediate 3-((1r-4r)-4-hydroxycyclohexa-2,5-dienyl)-2-oxopropanoic acid after a decarboxylation reaction catalyzed by BacA. BacB catalyzes the oxidation of this product to yield 2-oxo-3-(4-oxocyclohexa-2,5-dienyl)propanoic acid. The synthesis of l-anticapsin from 2-oxo-3-(4-oxocyclohexa-2,5-dienyl)propanoic acid would further require a ring epoxidation and a transamination reaction in the ketone group.