TABLE 1.
Identification of the protein components of the Sam68 RNP complex
The protein components of Sam68 RNP complex are identified by LC-MS/MS mass spectrometry.
Gene ID | Score | Protein name |
---|---|---|
Cancer, cell cycle, and proliferation | ||
10006 | 84 | Abl-interactor 1 |
4869 | 152 | B23 nucleophosmin |
8531 | 103 | Cold shock domain protein A |
1809 | 538 | Dihydropyrimidinase-like 3 |
10243 | 66 | Gephyrin |
3313 | 375 | Heat shock 70-kDa protein 98 (mortalin-2) |
3320 | 347 | Heat shock 90-kDa protein |
3065 | 71 | Histone deacetylase 1 |
9961 | 3.50E+05 | Major vault protein (Irp)a |
5340 | 45 | Plasminogen |
5154 | 50 | Platelet-derived growth factor receptor β precursor variant |
5315 | 370 | Pyruvate kinase (M2-PK)a |
6418 | 122 | SET translocation (myeloid leukemia-associated) |
7052 | 157 | Transglutaminase 2 isoform a |
7168 | 114 | Tropomyosin 1 |
7173 | 184 | Iropomyosin 3 |
7184 | 68 | Tumor rejection antigen (gp96) |
7415 | 145 | Valosin-containing protein |
Transcription, splicing, and RNA metabolism | ||
1975 | 49 | elF4B |
10146 | 77 | G3BPIa |
3309 | 376 | Heat shock 70-kDa protein 5 (glucose-regulated protein, 78 kDa) |
3182 | 104 | hnRNP A/B |
3183 | 84 | hnRNP C |
3184 | 141 | hnRNP Da |
3190 | 87 | hnRNP Ka |
3191 | 65 | hnRNP L |
10236 | 87 | hnRNP R |
4691 | 97 | Nucleolin |
6202 | 244 | Ribosomal protein S8 |
3921 | 121 | Ribosomal protein SA (67 kDa laminin receptor)a |
6176 | 50 | Ribosomal protein, large, P1 |
6181 | 87 | Ribosomal protein, large, P2a |
6421 | 60 | SFPQ proteina |
202559 | 73 | SLM-1 |
10656 | 96 | SLM-2 |
6426 | 275 | Splicing factor; arginine/serine-rich 1 |
6427 | 141 | Splicing factor; arginine/serine-rich 2 |
10492 | 163 | Synaptotagmin binding; cytoplasmic RNA interacting protein |
Cell adhesion and mobility | ||
58 | 184 | Actin αa |
60 | 206 | Actin βa |
70 | 127 | Actin γ |
2335 | 518 | Fibronectin 1a |
7431 | 118 | Vimentina |
a These proteins were also identified by quantitative mass spectrometry in SICs (38).