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. 2009 Sep 17;284(46):31903–31913. doi: 10.1074/jbc.M109.018465

TABLE 1.

Identification of the protein components of the Sam68 RNP complex

The protein components of Sam68 RNP complex are identified by LC-MS/MS mass spectrometry.

Gene ID Score Protein name
Cancer, cell cycle, and proliferation
    10006 84 Abl-interactor 1
    4869 152 B23 nucleophosmin
    8531 103 Cold shock domain protein A
    1809 538 Dihydropyrimidinase-like 3
    10243 66 Gephyrin
    3313 375 Heat shock 70-kDa protein 98 (mortalin-2)
    3320 347 Heat shock 90-kDa protein
    3065 71 Histone deacetylase 1
    9961 3.50E+05 Major vault protein (Irp)a
    5340 45 Plasminogen
    5154 50 Platelet-derived growth factor receptor β precursor variant
    5315 370 Pyruvate kinase (M2-PK)a
    6418 122 SET translocation (myeloid leukemia-associated)
    7052 157 Transglutaminase 2 isoform a
    7168 114 Tropomyosin 1
    7173 184 Iropomyosin 3
    7184 68 Tumor rejection antigen (gp96)
    7415 145 Valosin-containing protein

Transcription, splicing, and RNA metabolism
    1975 49 elF4B
    10146 77 G3BPIa
    3309 376 Heat shock 70-kDa protein 5 (glucose-regulated protein, 78 kDa)
    3182 104 hnRNP A/B
    3183 84 hnRNP C
    3184 141 hnRNP Da
    3190 87 hnRNP Ka
    3191 65 hnRNP L
    10236 87 hnRNP R
    4691 97 Nucleolin
    6202 244 Ribosomal protein S8
    3921 121 Ribosomal protein SA (67 kDa laminin receptor)a
    6176 50 Ribosomal protein, large, P1
    6181 87 Ribosomal protein, large, P2a
    6421 60 SFPQ proteina
    202559 73 SLM-1
    10656 96 SLM-2
    6426 275 Splicing factor; arginine/serine-rich 1
    6427 141 Splicing factor; arginine/serine-rich 2
    10492 163 Synaptotagmin binding; cytoplasmic RNA interacting protein

Cell adhesion and mobility
    58 184 Actin αa
    60 206 Actin βa
    70 127 Actin γ
    2335 518 Fibronectin 1a
    7431 118 Vimentina

a These proteins were also identified by quantitative mass spectrometry in SICs (38).