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. 2009 Sep 10;284(46):32126–32137. doi: 10.1074/jbc.M109.048629

FIGURE 9.

FIGURE 9.

Models for adaptor-assisted and direct Rsp5-Cps1 interaction. A, model for the Bsd2-facilitated interaction between Rsp5 and Cps1. Bsd2 PY motifs interact with Rsp5 WW domains to facilitate Cps1 ubiquitination. B, Rsp5 interacts directly with Cps1 leading to Cps1 ubiquitination. The Cps1 sorting sequence PVEKAPR interacts with the Rsp5 C-lobe in a manner that requires the Glu7 residue within the sorting sequence, while additional Cps1 residues interact with the Rsp5 N-lobe.