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Foci formation as observed in CellDetect® staining of BALB/3T3 cells
| Initiating treatment | Promoting treatment | Total No. of foci | No. of dishes with foci/No. of dishes examined | Foci/dish |
|---|---|---|---|---|
| None | None | 1 | 1/4 | 0.25 |
| None | TPA | 3 | 3/4 | 0.75 |
| MNNG | None | 2 | 2/4 | 0.5 |
| MNNG | TPA | 18 | 4/4 | 4.5 |
Treatment with both mutagen and TPA largely enhances type 3 foci formation
