| IP3R |
ER |
PM (65), Golgi (113), nucleus (115), secretory vesicles (118,119) |
IP3, Ca2+, ATP, cAMP, PKA, PKC, luminal chromogranin, Bcl-2, Bcl-XL, RACK1, Gβγ, NCS-1 (Mg2+, Ca2+, PIP2, IRBIT, calmodulin, ankyrin, ERp44) (111,198) |
| RyR |
ER |
PM (185), secretory vesicles (118,169), endosomes (170) |
Ca2+, cyclic ADP ribose, ATP, Ca2+-calmodulin-dependent protein kinase, PKA, FKBP12 (Mg2+, Ca2+, calmodulin) (199) |
| TPC1 |
lysosomes (233) |
PM (267) |
NAADP (233) |
| TRPP2 |
ER (47) |
PM (47) |
Ca2+, casein kinase 2, α-actinin, ATP (cytosolic H+) (268) |
| TRPM8 |
PM (269,270) |
ER (271) |
cold, depolarization, PIP2(272) (spermine) (273) |
| TRPC7 |
PM (274) |
TGN and Golgi (275) |
G-protein-coupled receptors, diacyglycerol (276) (calmodulin, cytosolic Ca2+) (277) |
| TRPV1 |
PM (278) |
ER (78) |
capsaicin, luminal H+, heat, ATP, PKA, protein kinase C (75,279) (PIP2) (279) |
| TRPA1 |
PM (280) |
|
cold, PIP2(281) |
| TRPML1 |
lysosomes, endosomes (282) |
PM (283) |
(Luminal H+) (282) |
| Cav
|
PM |
secretory vesicles (93) |
depolarization, PIP2, PKA, spermine (depolarization, arachidonic acid) (284,285) |
| NMDA receptor |
PM |
|
glutamate, glycine, PIP2 (extracellular: oxidation, H+, Mg2+, Zn2+) (286,287) |
| CNG channel |
PM |
|
cAMP, cGMP |
| P2X4 receptor |
PM |
lysosomes (51) |
ATP (extracellular H+) (288) |
| pannexin-1 |
PM |
ER (289) |
depolarization, mechanical stress, Ca2+ (ATP, cytosolic H+) (290) |
| connexins |
PM |
|
cytosolic Ca2+, mechanical stress, depolarization (extracellular: Ca2+, Mg2+; cytosolic H+) (290) |
| Orai1−3 |
PM |
|
STIM1, extracellular Ca2+ (cytosolic Ca2+) (147) |
| nicotinic receptor |
PM |
|
acetylcholine |
