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. Author manuscript; available in PMC: 2010 Sep 4.
Published in final edited form as: Cell. 2009 Sep 4;138(5):990–1004. doi: 10.1016/j.cell.2009.06.047

Figure 7. Model for srGAP2 regulated membrane protrusion in neuronal migration.

Figure 7

(A–F) Representative images of optically isolated neurons translocating radially through layer 5/6 following electroporation at E15 (+5div) with indicated srGAP2 constructs containing a F-BAR domain.

(G–H) Hypothetical model of the molecular mechanisms underlying srGAP2 function in membrane protrusion during neuronal migration and morphogenesis (G). Summary of srGAP2 effects on neuronal migration and morphogenesis during cortical development (H). See text for details.