Figure 1.

(A) Proliferative T cell responses of LNCs from HLA-DR3.Ab⁰ mice immunized with BCG (10 μg), hsp65 (10 μg), p1–20 (100 μg), or PBS, in IFA. Proliferation is indicated in delta cpm (mean cpm in experimental wells − mean cpm in control wells without Ag). (B) Percentage inhibition of proliferative T cell responses by mAb specific for HLA-DR, mouse CD4, and mouse CD8, H2-Eα, and H2-Eβ LNCs of BCG-immunized mice were challenged in vitro with BCG, hsp65, or p1–20 in the presence of indicated mAb. (C) IFN-γ production by DR3-restricted LNCs from DR3.Ab⁰ mice immunized with BCG, hsp65, or p1–20. The in vitro challenge is indicated in the key.