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. 2009 Dec 10;28(1):150. doi: 10.1186/1756-9966-28-150

Figure 5.

Figure 5

We used the tunel stain to investigate the effect of HIF-1alpha and SOCS1 on cell apoptosis and the apoptosis rate was calculated in all the experimental groups. (A) The background was clear and the apoptotic NCI-H446 nucleuses were stained yellow and normal nucleuses were stain blue(tunel stain × 400) (B) The effect of HIF-1alpha and SOCS1 on apoptosis of SCLC cells after transfection for 8 d (*p < 0.05 Ad5-HIF-1alpha/siSOCS1 group vs. Ad5-HIF-1alpha group; **p < 0.05 Ad5-HIF-1alpha/siSOCS1 group vs. Ad5-siSOCS1 group; ***p < 0.01 Ad5-si HIF-1alpha/SOCS1 group vs. Ad5-siHIF-1alpha group; ****p < 0.05 Ad5-si HIF-1alpha/SOCS1 group vs. Ad5-SOCS1 group).