Table 2.
SNPs associated with asthma or atopy with a FDR of 5% in the pooling-based GWA
| SNP | Chromosome | Position | Comparison | p value | fAco-fAca | Region | Saturation |
|---|---|---|---|---|---|---|---|
| rs2501618 | 1 | 178225432 | Atopy vs. controls | 1.26 × 10-7 | 0.26 | CEP350 | No |
| rs4952590 | 2 | 42130425 | Atopy vs. controls | 4.63 × 10-7 | 0.19 | SGK493 (LOC91461) | Yes |
| rs7629719 | 3 | 131642624 | Atopy-Asthma vs. controls | 1.11 × 10-7 | 0.21 | COL29A1 (COL6A5) | Yes |
| rs9292961 | 5 | 20975886 | Atopy vs. controls | 5.38 × 10-7 | 0.3 | Segmental Duplications | No |
| rs9376221 | 6 | 137034072 | Atopy vs. controls | 3.94 × 10-7 | 0.25 | MAP3K5 (ASK1) | Yes |
| rs7843085 | 8 | 33235086 | Atopy vs. controls | 3.93 × 10-7 | 0.26 | NT_007995.50 | Yes |
| rs13273924 | 8 | 33246541 | Atopy vs. controls | 7.56 × 10-7 | 0.26 | NT_007995.50 | Yes |
| rs2330183 | 21 | 45777720 | Atopy vs. controls | 1.59 × 10-7 | 0.28 | SLC19A1 | Yes |
fAco (allele frequency in controls); fAca (allele frequency in cases); CEP350: centrosomal protein 350 kDa; SGK493: protein kinase-like protein SgK493; COL29A1: collagen, type XXIX, alpha 1; MAP3K5: mitogen-activated protein kinase kinase kinase 5; ASK1: apoptosis signal-regulating kinase 1; SLC19A1: solute carrier family 19 (folate transporter), member 1