Table 3.

Summary of the SNPs significantly associated with atopy at an individual level

					ECHRS Atopy vs. controls
SNP	Gene	MAF	Chromosome	Position (build36)	Pooling	Replication	Combined
rs11124858*	SGK493	0.367	2	42113828	0.0021	0.0318	0.0007†
rs13409978*	SGK493	0.122	2	42119206	0.0007†	0.0124	0.0001†
rs4952590**	SGK493	0.141	2	42130425	0.0001†	0.0008†	1.9 × 10-6†
rs1440095	SGK493	0.379	2	42143170	0.0098	0.1078	0.0105
rs10934938	COL29A1	0.23	3	131596325	0.1158	0.0291	0.0056
rs9402839*	MAP3K5	0.138	6	137036903	0.0355	0.0524	0.0099
rs9494554**	MAP3K5	0.095	6	137038675	0.0306	0.0035	0.0005†
rs12483377*	COL18A1	0.108	21	45755537	0.0046	0.0607	0.0030

*SNPs found associated in the pooling-based GWA or their perfect tags (r² = 0.8) used as substitutes in the genotyping design.

**SNPs that remained significant after a 5% FDR in the pooling-based GWA

^†P-values that remain significant after Bonferroni correction (46 SNPs, p ≤ 0.001)