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. 2009 Nov 21;9:407. doi: 10.1186/1471-2407-9-407

Table 3.

Incidence rate ratio for colorectal cancer for combinations of MDR1 genotypes

	IRR^a(95% CI) (N_case/N_sub-cohort)
	MDR1 C3435T
MDR1 G-rs3789243-A	CC		CT		TT
GG	1.38	(0.31-6.15)	1.16	(0.66-2.06)	1.00^b	-
N_case/N_sub-cohort	(3/6)		(27/68)		(52/153)
GA	2.20	(1.22-3.96)	1.52	(1.01-2.29)	1.72	(1.06-2.81)
N_case/N_sub-cohort	(32/42)		(110/234)		(55/92)
AA	1.80	(1.06-3.05)	1.38	(0.82-2.32)	1.48	(0.58-3.75)
N_case/N_sub-cohort	(39/72)		(38/85)		(8/20)

^aAdjusted for status of HRT, smoking status, alcohol, dietary fibre, red meat and BMI.

^bThe most prevalent double homozygous genotype was used as reference.