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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: J Biomed Mater Res A. 2010 Feb;92(2):667–682. doi: 10.1002/jbm.a.32368

Figure 2.

Figure 2

T-cell and B-cell activation: Flow cytometric analysis of a highly Co reactive subject (SI>40) is shown to contain both T-cell (47% CD4+CD25+) and B-cell (59% CD19+CD69+) activation at 48 hours. Control activation for non-challenged T-cells and B-cells from this subject was below 2.5%. An increase in T-cell and B-cell activation is also demonstrated with Ni where a 11% and 6% increase in activation, respectively, is associated with a SI>5. Subject A: Group 1, 43 year old female with a history of dermal sensitivity to jewelry.