Table 1. Results of single marker analyses for SNPs in ZNF804A, NOS1 and RGRIP1L.

2-tailed p-values are shown for all tests and 1-tailed p-values are shown for the three previously reported SNPs

Locus	Mbp	SNP	Allele	fCases	fControls	Allelic OR (95% CI)	CA (Z)	1t p	2t p	HWE p
Chr 2 ZNF804A	185.19	rs13393273	G	0.44	0.4	1.17 (1.01–1.36)	−2.107		0.0351	0.2684
	185.19	rs17508595	G	0.31	0.27	1.21 (1.02 − 1.43)	−2.285		0.0230	0.0809
	185.20	rs12613195	C	0.7	0.67	1.15 (0.98 − 1.35)	−1.687		0.0917	0.7266
	185.22	rs12693385	T	0.57	0.54	1.11 (0.96 − 1.29)	−1.421		0.1553	0.5129
	185.24	rs7597593	T	0.44	0.38	1.28 (1.10 − 1.49)	−3.212		0.0013	0.8647
	185.26	rs1480481	C	0.41	0.35					1.13E-10
	185.41	rs7605689	T	0.81	0.79	1.12 (0.93 − 1.35)	−1.222		0.2216	0.4775
	185.47	rs3931790	T	0.83	0.81	1.10 (0.91 − 1.34)	−0.998		0.3181	0.8894
	185.48	rs7603001	A	0.51	0.47	1.16 (1.00 − 1.34)	−1.929		0.0537	0.7286
	185.49	rs1344706	A (+)	0.65	0.61	1.20 (1.03 − 1.40)	−2.279	0.0113	0.0227	0.0153
	185.51	rs4667001	G	0.44	0.41	1.14 (0.98 − 1.32)	−1.661		0.0966	0.6028
	185.51	rs12477430	A	0.33	0.29	1.17 (1.00 − 1.38)	−1.909		0.0563	0.7632
	Mbp	SNP	Allele	fCases	fControls	Allelic OR (95% CI)	CA (Z)	1t p	2t p	HWE p
Chr 12 NOS1	116.19	rs6490121	A	0.66	0.65	1.07 (0.91 − 1.25)	−0.806	0.210	0.420	0.7591
	Mbp	SNP	Allele	fCases	fControls	Allelic OR (95% CI)	CA (Z)	1t p	2t p	HWE p
Chr 16 RGRIP1L	52.21	rs9922369	A (+)	0.03	0.02	1.57 (0.91 − 2.71)	−1.631	0.0515	0.1029	1

Note that rs1344706 is here reported on the genomic (+) strand, where its alleles are A or C. Associated SNPs are shown in bold, (+) indicates the same allele as observed in the original study. Mbp: physical position in megabasepairs; f_{Cases/Controls}: Frequency of indicated allele in cases and controls respectively; CA (Z): Cochran-Armitage test statistic; 1t p, 2t p: one- and two-tailed p-values respectively; HWE p: Hardy-Weinberg equilibrium p-value.