Table 2. Classification of proteins identified in the Mtb pupylome.
Classification: | No. with pupylated peptide: | Percent of pupylome1: | Percent of predicted proteome2: |
Intermediary metabolism | 25 | 45 | 22 |
Conserved hypotheticals | 7 | 13 | 26 |
Lipid metabolism | 8 | 15 | 6 |
Information pathways | 4 | 7 | 6 |
Cell wall, membrane- | 4 | 7 | 18 |
associated | |||
Detoxification/virulence | 6 | 11 | 3 |
Regulators | 1 | 2 | 5 |
Percentage of proteins of this class identified over the total number of pupylated proteins identified by MS.
Percentage of this class of proteins in the total predicted Mtb proteome.