Table 2. Comparison of cytokine production capacities of DP T cells with that of SP subpopulations by FACS analysis.
| CD4 | CD8 | DP | ||
| CYTOKINE PRODUCTION | TNF-α | 63+/−12 | 79+/−12 | 82+/−10 |
| IFN-γ | 32+/−16 | 49+/−29 | 46+/−13 | |
| IL-2 | 28+/−11 | 35+/−17 | 48+/−14 | |
| IL-4 | 22+/−10 | 23+/−5 | 40+/−11* | |
| IL-5 | 2+/−1 | 5+/−2 | 21+/−7*** | |
| IL-13 | 28+/−10 | 35+/−11 | 75+/−12*** | |
| GM-CSF | 48+/−22 | 53+/−22 | 74+/−11 |
Data are expressed as mean % of intracellular cytokine secreting cells in response to anti-CD3 stimulation (n = 5). Significance increase of cytokines production by DP T cells was evaluated by Tukey-Kramer's test. *P<0.05,***P<0.001. No cytokine production was observed by unstimulated subpopulations.