Table 1.

Success and failure rates after therapeutic intervention in children with liver-biopsy-proven NAFLD n (%)

	Lifestyle intervention	Vitamin E	Metformin
n	29	25	28
Complete success (all endpoints)	11 (38)	9 (36)	2 (7)
Partial success
Serum ALT normalization	23 (79)	13 (52)	23 (75)
HOMA-IR ≤ 1 restoration	11 (38)	9 (36)	2 (7)
NAS amelioration	19 (65)	17 (68)	16 (57)
Complete failure	4 (14)	8 (32)	2 (7)

NAFLD: Nonalcoholic fatty liver disease; HOMA-IR: Homeostatic model assessment of insulin resistance; NAS: NAFLD activity score; ALT: Alanine transaminase.