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. Author manuscript; available in PMC: 2009 Dec 24.
Published in final edited form as: Arch Gen Psychiatry. 2009 Sep;66(9):938–946. doi: 10.1001/archgenpsychiatry.2009.115

Table 2.

Cerebral Blood Volumes by Subregion

Mean (SD)
Subregion Control Ultra–High-Risk Schizophrenia
Anterior hippocampus
 Entorhinal cortex 1.56 (0.84) 1.41 (0.92) 1.29 (1.03)
 Subiculum 1.76 (0.88) 1.60 (0.98) 2.50 (1.38)a
 CA1 subfield 1.26 (0.47) 1.48 (0.49) 1.99 (0.82)b
 CA3 subfield 1.86 (1.18) 1.69 (0.82) 1.93 (1.48)
 Dentate gyrus 1.51 (1.02) 0.78 (0.88) 1.47 (1.00)
 Posterior hippocampus 1.98 (0.52) 2.08 (0.51) 1.88 (1.10)
Prefrontal cortex
 Gyrus rectus 2.13 (0.96) 2.08 (0.60) 1.92 (0.96)
 Medial orbitofrontal cortex 1.36 (1.06) 2.03 (0.84) 2.51 (1.00)b
 Dorsolateral prefrontal cortex 2.35 (0.56) 2.09 (0.60) 1.79 (0.84)c
Ventral striatum
 Caudate 1.78 (0.43) 1.70 (0.63) 2.05 (1.16)
 Nucleus accumbens 1.88 (0.52) 2.16 (0.71) 2.04 (1.16)
 Putamen 2.32 (0.52) 1.98 (0.64) 2.07 (0.84)
Amygdala
 Dorsal nucleus 1.30 (1.02) 1.41 (1.61) 1.22 (1.59)
 Basolateral nucleus 1.04 (1.03) 1.49 (0.55) 1.50 (1.03)
a

P < .10 for controls vs patients with schizophrenia by analysis of variance.

b

P < .01 for controls vs patients with schizophrenia by analysis of variance.

c

P < .05 for controls vs patients with schizophrenia by analysis of variance.