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. Author manuscript; available in PMC: 2010 Dec 10.
Published in final edited form as: J Med Chem. 2009 Dec 10;52(23):7512–7527. doi: 10.1021/jm900016t

Scheme 4.

Scheme 4

Synthesis of compounds 37 and 38a

a Reagents and reaction conditions: (a) (37) MCPBA (1 equiv), CHCl3,25 °C, 1.5 h, 99%; (b) (38) MCPBA (2 equiv), CHCl3,25 °C, 1.5 h, 96%.