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. Author manuscript; available in PMC: 2010 Dec 10.
Published in final edited form as: J Med Chem. 2009 Dec 10;52(23):7512–7527. doi: 10.1021/jm900016t

Table 3.

Effects of 24,27–29,36,39, and 41 on HeLa and HCT116/chr3 Cell Proliferation

% of cell proliferationa,b
HeLac
 HCT116/chr3d
compd 0.5 μM 1 μM 0.5 μM 1 μM
24 47±0.5 56±1.2 60±0.8 60±3.9
27 53±0.1 60±0.1 57±0.9 62±1.9
28 41±1.1 47±0.4 59±0.2 66±3.5
29 52±0.4 45±1.6 51±4.6 51±1.6
36 57±1.4 43±0.3 63±1.0 54±1.0
39 55±0.7 54±0.3 57±3.4 55±1.2
41 52±0.7 51±0.2 69±6.7 69±0.3
a

Data are expressed as % mean values ± SD; control cells are considered as 100% (MTT method).

b

Treatments were performed for 24 h at the indicated concentrations.

c

HeLa cervical cancer cells.

d

HCT116/chr3 human colon cancer cells.