Table 4.
IC50 ± SD (nM) |
|||
---|---|---|---|
compd | HEKb | M14c | U937d |
24 | 220±3 | 194±3 | 100±3 |
27 | 189±5 | 155±9 | 177±10 |
28 | 131±3 | 78±3 | 191±7 |
29 | 160±5 | 120±10 | 159±10 |
36 | 128±7 | 111±6 | 122±6 |
39 | 140±1 | 100±5 | 155±10 |
41 | 181±3 | 137±5 | 189±5 |
Growth inhibition of the indicated cell lines (MTT method); incubation time was 48 h.
HEK, human embryonic kidney 293 cells;
M14, human melanoma cells;
U937, human leukemic monocyte lymphoma cells.