Figure 10.

All rescued rNeph/mNeph^−/− male mice were smaller in size, infertile, and their genitals showed anatomical malformations at the age of 5 to 6 weeks. A and B show the differences in body size. C and D show the smaller size of the male genitals of rNeph/mNeph^−/− mice. E and F show that testicles had not descended and seminal vesicle formation was severely impaired in rNeph/mNeph^−/− males. These changes have been highlighted with arrows in D and F.