Table 1.

Genotype Ratios, Body Weights, and Urine Protein Concentrations in the rNeph/mNeph Mouse Line

Genotype	Number of mice birthed	Body weight 1w (g)	Body weight 6w (g)	Protein in urine 3w (g/L)	Protein in urine 6w (g/L)
rNeph/mNeph+/+	18/72	4.7 ± 0.7	25.4 ± 5.3	0.3–1.0	0.3–1.0
rNeph/mNeph+/−	40/72	5.1 ± 0.7	25.7 ± 4.8	0.3–1.0	0.3–1.0
rNeph/mNeph−/−	14/72	2.2 ± 0.5***	15.2 ± 6.4***	≥3.0	≥3.0

Statistical significant differences (n = 5 to 10) after LSD test compared with rNeph/mNeph^+/+ group;

^***P < 0.001.