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. 2010 Jan;176(1):74–84. doi: 10.2353/ajpath.2010.090678

Figure 6.

Figure 6

Deletion of 12/15 LOX up-regulates key regulators of inflammatory neovascularization. Corneas after 48 hours of chronic injury were collected from 12/15-LOX KO and matched congenic wild-type mice (n = 4). mRNA expression was quantified for HO-1, VEGF-A, sFLT1, and FLT4 using a Step One Plus QPCR system (Applied Biosystems). RNA expression for each gene was calculated using relative quantity (RQ) compared with a mouse positive mRNA control with the ΔΔCT method and β-actin as a reference gene. Data are expressed as fold change compared with the mouse positive mRNA control (n = 4, *P < 0.05).