Figure 3.

A: Representative histological sections of the ear pinnae from stressed wild-type, E-, P-, and L-selectin^−/− mice 48 hours after oxazolone elicitation. The sections were stained with H&E. The improvement of edema and leukocyte infiltration was noticed only in the dermis of ear pinnae from the stressed L-selectin^−/− mice as compared with the stressed wild-type mice. Original magnification, ×100. B: Total ear thickness in CH responses in stressed wild-type, E-, P-, and L-selectin^−/− mice 48 hours after oxazolon elicitation. All values represent the mean ± SEM of results obtained from 8 to 10 mice. Stressed L-selectin^−/− mice only showed a significant improvement in ear thickness as compared with stressed wild-type mice in CH responses (**P < 0.01).