Figure 7.

A: Representative histological sections of CH responses in the ear pinnae from stressed wild-type mice with or without injection of NK1R antagonist 48 hours after oxazolone elicitation. The sections were stained with H&E. Original magnification, ×100. An improvement of edema and leukocyte infiltration was shown in the dermis of ear pinnae from stressed CH mice injected with NK1R antagonist as compared with stressed CH mice without injection. B: Total ear thickness in stressed CH mice with or without injections of NK1R antagonist 48 hours after oxazolon elicitation. The ear thickness was measured 48 hours after oxazolone elicitation. All values represent the mean ± SEM of results obtained from 8 to 10 mice. Stressed CH mice injected with NK1R antagonist showed a significant decrease in ear thickness as compared with stressed CH mice without injection (**P < 0.01).