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Active MMP-2 and MMP-9 induces angiogenesis in a rat corneal micropocket assay. Representative photographs of rat corneas (n ≥ 5 for each treatment) at 7 days after implantation of pellets containing buffer (control, A), pro-MMP-9 (100 ng, B), active MMP-9 (100 ng, C), pro-MMP-2 (100 ng, D), and active MMP-2 (E). Mean vessel extension (F) and area (mm2G) were calculated as described in Materials and Methods. **P = 0.003, *P = 0.008.
