Table 1.
Characteristics of the Patients
| DR n = 20 | DM-PAD n = 20 | Normal control n = 20 | P value | |
|---|---|---|---|---|
| Age (yr) | 69.5 ± 7.5 | 65.8 ± 6 | 67.7 ± 4.5 | NS |
| Sex M (n/%) | 9(45%) | 12/(60%) | 10/(50%) | NS |
| Duration of diabetes (yr) | 11.3 ± 5.0 | 14.50 ± 6.0 | / | |
| BMI (kg/m2) | 24.2 ± 1.2 | 23.7 ± 3.1 | 23.2 ± 2.3 | NS |
| Laboratory testing | ||||
| Fasting glucose (mmol/L) | 7.2 ± 4.3 | 7.9 ± 2.8 | 5.1 ± 1.2* | <0.01 |
| HbA1c (%) | 8.5 ± 1.2 | 9.2 ± 1.7 | / | |
| Total cholesterol mg/dl | 184.6 ± 3.8. | 187.2 ± 5.2 | 180.0 ± 10.5 | NS |
| LDL-C, mg/dl | 114.2 ± 5.2 | 116.2 ± 3.4 | 110.3 ± 4.8 | NS |
| HDL-C, mg/dl | 47.2 ± 1.6 | 45.6 ± 1.8 | 51.2 ± 1.3 | NS |
| Triglycerides, mg/dl | 133.8 ± 11.2 | 145.8 ± 9.6 | 133.2 ± 10.5 | NS |
| Clinical history | ||||
| Hypertension | 13 | 15 | 13 | NS |
| CAD | 9 | 12 | 10 | NS |
| Smoker | 3 | 5 | 5 | NS |
| Medications | ||||
| Insulin | 5 | 7 | / | |
| Oral Antidiabetics | 20 | 20 | / | |
| TZDs | 5 | 7 | / | NS |
| Statins | 12 | 11 | 13 | NS |
| ACE-inhibitors | 3 | 4 | 4 | NS |
| Other hypotensive drugs | 11 | 13 | 10 | NS |
NS: not statistic significant; dashes denote not applicable.