TABLE 3.

Insulin signaling proteins are modulated in adipose and whole blood during endotoxemia

Gene	Adipose mRNA expression			Blood mRNA expression
	Maximal percent change	Time (h)	ANOVA P value	Maximal percent change	Time (h)	Mixed-effects model P value
Insulin receptor	−25	12	0.26	−20	2	<0.001
IRS-1	−47	4	0.03	−53	4	0.03
IRS-2	−25	4	0.36	+230	12	<0.001
IRS-3	ND	—	—	−50	4	<0.001
GLUT4	−24	12	0.33	−25	12	0.02

ND, not detected.