TABLE 2.
Multivariate Cox regression analysis including factors that influence the recurrence risk in offspring of parents with late-onset type 1 diabetes
| Univariate analyses |
Multivariate analyses (full model) |
|||||
|---|---|---|---|---|---|---|
| Variable | HR | 95% CI | P | Adjusted HR | 95% CI | P |
| Sex of diabetic parent | ||||||
| Female | 1.00 | — | ||||
| Male | 0.81 | 0.54–1.21 | 0.30 | 0.78 | 0.52–1.18 | 0.23 |
| Sex of offspring | ||||||
| Female | 1.00 | — | 1.00 | — | ||
| Male | 0.88 | 0.59–1.31 | 0.52 | 0.87 | 0.58–1.30 | 0.49 |
| Age at onset of diabetes in parents | ||||||
| Continuous | 0.97 | 0.93–1.00 | 0.06 | 0.97 | 0.91–1.04 | 0.42 |
| Year of birth of offspring | ||||||
| Continuous | 1.04 | 1.00–1.08 | 0.06 | 1.02 | 0.95–1.10 | 0.57 |
| Parental age at delivery | 1.01 | 0.96–1.05 | 0.81 | 1.01 | 0.94–1.09 | 0.78 |
No significant interaction terms.