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. 2009 Oct 21;59(1):43–50. doi: 10.2337/db09-1128

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© 2010 American Diabetes Association

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 2. — POA injection of insulin increased fatty acid utilization and BAT activity A: The 6-h profile of RER of mice treated with vehicle of 0.03 IU insulin in the POA, demonstrating that insulin injection decreased RER, indicating an elevation of fatty acid utilization. B: The 3-h profile of PET/CT of ¹⁸F-FDG uptake in rats injected with vehicle or 0.03 IU insulin in the POA. Top panel shows the representative PET/CT; squared in dotted lines is the area investigated after treatment with insulin or vehicle shown below. The anatomical position of BAT is indicated with an arrow. C: The 3-h profile quantification of ¹⁸F-FDG uptake into BAT after insulin treatment as indicated. Data are presented as means ± SE. *P < 0.05.