Table 2.
SIGT |
NHANES III |
NHANES 2005–2006 |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
All subjects | IFG (±IGT) | IGT (±IFG) | IFG + IGT | All subjects | IFG (±IGT) | IGT (±IFG) | IFG + IGT | All subjects | IFG (±IGT) | IGT (±IFG) | IFG + IGT | |
n | 1,581 | 2,014 (weighted) | 1,111 (weighted) | |||||||||
Age <60 years | 84 | 79 | 76 | 77 | 66 | 62 | 51 | 48 | 80 | 72 | 60 | 51 |
BMI ≥35 kg/m2 | 22 | 27 | 30 | 38 | 9 | 11 | 11 | 12 | 16 | 23 | 27 | 30 |
Family history of diabetes | 46 | 49 | 54 | 55 | 28 | 29 | 31 | 34 | 36 | 39 | 50 | 51 |
Triglycerides ≥150 mg/dl | 13 | 18 | 18 | 21 | 37 | 45 | 53 | 50 | 28 | 37 | 47 | 55 |
Reduced HDL cholesterol* | 47 | 54 | 57 | 64 | 40 | 44 | 47 | 50 | 21 | 23 | 29 | 29 |
Hypertension† | 49 | 63 | 68 | 69 | 41 | 44 | 57 | 54 | 28 | 37 | 42 | 49 |
A1C <6.0% | 7 | 10 | 12 | 18 | 8 | 9 | 11 | 13 | 6 | 9 | 11 | 17 |
≥1 risk factor | 99 | 99 | 99 | 99 | 95 | 96 | 96 | 96 | 74 | 83 | 94 | 96 |
Metformin indicated‡ | 8.1 | 31.0 | 52.7 | 99.2 | 9.1 | 28.6 | 57.3 | 96.2 | 8.7 | 28.2 | 61.7 | 96.2 |
Data are %. Glucose tolerance categories: IFG (±IGT), IFG with or without IGT; IGT (±IFG), IGT with or without IFG; IFG + IGT, both IFG and IGT.
*Reduced HDL cholesterol defined as ≤40 mg/dl in men and ≤50 mg/dl in women.
†Hypertension defined by any of the following: history of hypertension, systolic blood pressure ≥130 mmHg, or diastolic blood pressure ≥85 mmHg.
‡Metformin indicated per the ADA consensus statement (8) criteria of the presence of both IFG and IGT and one of the following diabetes risk factors: age <60 years, BMI ≥35 kg/m2, family history of diabetes, elevated triglycerides, reduced HDL cholesterol, and A1C >6.0%. Risk factors for diabetes that were not specifically defined by the ADA were categorized according to the AHA/NHLBI diagnostic criteria for metabolic syndrome (12): presence of hypertension by history, systolic blood pressure >130 mmHg or diastolic blood pressure >85 mmHg, triglyceride level ≥150 mg/dl, and HDL cholesterol <40 mg/dl in men and <50 mg/dl in women.