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. Author manuscript; available in PMC: 2011 Jan 15.
Published in final edited form as: J Infect Dis. 2010 Jan 15;201(2):190–198. doi: 10.1086/649228

Figure 1.

Figure 1

Figure 1

Figure 1

Microneedle coated with influenza vaccine. (A) Image of a 5-microneedle array (scale bar = 500 μm). Bright-field (B, D) and fluorescence (C, E) micrographs of a microneedle coated with red-fluorescent inactivated influenza virus before (B, C) and 10 min after (D, E) insertion into human cadaver skin (scale bar = 200 μm). Histologic section of human cadaver skin fixed after insertion of a vaccine-coated microneedle imaged by (F) bright-field microscopy showing skin deformation and needle track across epidermis and into superficial dermis and (G) fluorescence microscopy showing deposition of red-fluorescent vaccine coating in skin (scale bar = 200 μm).