Table 2.
Metastatic RCC of head and neck region and their characteristics
| Case # | Mets | Present | Age at Dx | Year at mets | Survival (years) | Tob. |
|---|---|---|---|---|---|---|
| 1 | Frontal lobe | HA, LUE Numbness, weakness | 24 | 4 | 17a | − |
| 2 | Cerebellum | HAb, N/V, blurry vision | 51 | 0 | 5 | + |
| 3 | Frontal lobe, mandible, scalp | Cystic lesions in the scalpb | 55 | 0 | 1 | + |
| 4 | Frontal lobe | Frontal HA, memory loss | 53 | 1 | 3 | − |
| 5 | Frontal, occipital lobes, cerebellum | Dizzinessb, dysarthria, dysphagia | 58 | 0 | 1 | + |
| 6 | Parotid | Parotid mass | 67 | 1 | 14a | + |
| 7 | Eye | c | 55 | 11 | 14 | + |
| 8 | Tongue | Tongue cyst | 27 | 0 | 1 | − |
| 9 | Brain | HA | 62 | 0 | <1 | + |
| Case # | Pathology | Other mets | Para-neoplastic syndromes | Treatments |
|---|---|---|---|---|
| 1 | Poorly differentiated carcinoma, staining for GFAP | Lung | None | Right frontal lobe craniotomy, nephrectomy, immune therapy, chemotherapy |
| 2 | Poorly differentiated (grade III), | Bone marrow, liver | None | Nephrectomy, posterior fossa craniotomy, hepatic wedge resection, chemotherapy, XRT |
| 3 | c | Adrenal, lungs, liver, skin | Hypercalcemia | IL-2, IFN a, XRT |
| 4 | Clear cell type (grade II) | None | Hypercalcemia | Nephrectomy, craniotomy |
| 5 | Clear cell (not graded) | Lungs | Hypercalcemia | XRT |
| 6 | Moderately well differentiated (grade II) | Colon | Polycythemia, hypercalcemia | Nephrectomy, colectomy |
| 7 | c | Bone | None | Nephrectomy, XRT, eye enucleation |
| 8 | Grade III | Spine, lung, liver | Hypercalcemia | XRT, nephrectomy |
| 9 | Diagnosed by FNA | Bone, lungs | Hypercalcemia | XRT |
aStill alive
bCancer presented with mets
cInitial diagnosis and work up at another institution, further records not available