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PSGL-1(HT) sequence compared to wild-type PSGL-1. Binding site for mAbs KPL-1 and PL-1 are indicated by straight lines. 6X Histidine-Thrombin cleavage site shown in shaded box substitute for selected amino acids in wild type molecule as indicated. Arrow denotes the thrombin cleavage site. *denotes site for tyrosine sulfation. Bold, italicized T denotes unique site for O-linked glycosylation.
