Table 4.

Brain regions in which greater activity for the Social Change > No Change correlated with Cognitive and Affective Empathy.

Social Change – No Change Social	R/L	BA	MNI Coordinates X, Y, Z	T value	Cluster Size
Social Change vs. No Change Correlated with Cognitive Empathy
Frontal Cortex:
Inferior Frontal Gyrus – Opercularis	L	44	-50, 10, 12	4.2	16
Anterior Insula	L	48	-38, 2, 8	5.6	50
Medial Orbital Frontal Cortex (MOFC)	R	11	4, 24, -24	5.9	199
Medial Orbital Frontal Cortex (MOFC)	L	11	-6, -54, -14	5.2	77
Medial Orbital Frontal Cortex (MOFC)	L	11	-10, 32, -16	4.4	43
Middle Frontal Gyrus (DLPFC)	L	6	-18, 18, 42	4.8	95
Supplementary Motor Area	R	6	14, -54, 4	5.3	68
Temporal Cortex
Superior Temporal Sulcus	R	21,22	52, -28, 0	5.2	25 #
Middle Temporal Gyrus	R	37	50, -64, 0	4.2	13
Middle Temporal Gyrus	R	37	42, -54, 4	5.4	49
Middle Temporal Gyrus	L	37	-44, -56, 0	7.7	178*
Hippocampus	L		-28, -40, 4	5.8	457
Parietal & Occipital Cortices
Supramarginal Gyrus (Somatosensory Related Cortex (SRC))	L	40	-44, -28, 28	5.9	89
Postcentral Gyrus (SCI)	L	3	-20, -30, 48	5.5	87
Postcentral Gyrus (SCI)	L	3	-20, -40, 54	4.4	21
Middle Cingulate Gyrus	R	23	16, -30, 40	4.5	23
Subcortical & Cerebellar
Thalamus	R		20, -26, 8	5.7	75
Social Change vs. No Change Correlated with Affective Empathy
Precentral Gyrus	R	6,44	46, 2, 28	5.1	24
Middle Frontal Gyrus	L	9, 46	-24, 56, 34	4.7	28
Superior Parietal Lobe – Intraparietal Sulcus	L	7	-16, -70, 48	7.5	51

^*Peak activation is significant when corrected for multiple comparisons (FWE, p<.05) within the region of interest using the Small Volume Correction (SVC) tool in SPM

^#Peak activation is significant when corrected for multiple comparisons with False Discovery Rate, p<.05 within the region of interest using the Small Volume Correction (SVC) tool in SPM