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. 2009 Jul 6;78(1):477–485. doi: 10.1128/IAI.00941-08

FIG. 1.

FIG. 1.

Antibody responses in BALB/c or C57BL/6J mice immunized with each of the four constructs of MSP3-1. Mice were immunized with MSP3-1(a-f) (□), MSP3-1(b-f) (▪), MSP3-1 LSP(a-d) (░⃞), and MSP3-1 LSP(b-d) (▤). The immunogens were administered at regular intervals of 2 weeks. Sera were collected after two to six immunizations and tested by ELISA on the MSP3-1b (left column), MSP3-1c (center column), and MSP3-1d (right column) peptides. (A) Comparison of IgG responses elicited in MSP3-1(a-f)- and MSP3-1 LSP(a-d)-immunized mice to peptides MSP3-1b (a), MSP3-1c (b), and MSP3-1d (c). (B) Comparison of IgG responses elicited in MSP3-1(a-f)- and MS3-1(b-f)-immunized mice to peptides MSP3-1b (a), MSP3-1c (b), and MSP3-1d (c). (C) Comparison of IgG responses elicited in MSP3-1 LSP(a-d)- and MSP3-1 LSP(b-d)-immunized mice to peptides MSP3-1b (a), MSP3-1c (b), and MSP3-1d (c). The results are expressed as mean ELISA titers ± the standard deviation (SD) in groups of five mice. Titers lower than 50 are considered negative. A nonparametric statistical analysis was performed; P values of <0.05 are indicated by an asterisk.