TABLE 1.
Organ | Mice (n = 4) | DPIb | No. of CFU/organ (105) (mean ± SEM) |
---|---|---|---|
Lung | WTc | 2 | 1.31 ± 0.263 |
4 | 39.8 ± 9.34 | ||
CD14−/− | 2 | 2.89 ± 1.64 | |
4 | 35.7 ± 4.45 | ||
Spleen | WT | 2 | 0.408 ± 0.320 |
4 | 518 ± 114 | ||
CD14−/− | 2 | 0.101 ± 0.0327 | |
4 | 619 ± 63 |
Mice were challenged with 50 CFU of F. tularensis SchuS4 intranasally.
DPI, day postinfection.
WT, wild type.