TABLE 1.
Demographic, clinical, and laboratory characteristics of the study participantsa
| Characteristic | Result |
P | |
|---|---|---|---|
| Non-SMA | SMA | ||
| No. of participants | 302 | 184 | N/A |
| Gender [no. (%)] | |||
| Male | 158 (52.3) | 91 (49.5) | 0.302b |
| Female | 144 (47.7) | 93 (50.5) | |
| Age (mo) | 11.0 (10.0) | 8.0 (7.0) | 0.001c |
| Axillary temp (°C) | 37.5 (1.7) | 37.4 (1.5) | 0.307c |
| Hemoglobin (g/dl) | 8.1 (2.7) | 4.9 (1.3) | 0.001c |
| RBC count (1012/liter) | 3.71 (1.29) | 2.11 (0.89) | 0.001c |
| Reticulocyte production index, RPI | 1.51 (2.02) | 1.12 (1.77) | 0.007c |
| WBC count (103/μl) | 11.05 (5.80) | 13.95 (9.85) | 0.001c |
| Parasite density (μl) | 20,612 (49,528) | 16,287 (34,322) | 0.081c |
| HDP (no. [%]) | 197 (65.2) | 105 (57.1) | 0.054b |
a
Data are median (IQR) unless otherwise stated. Abbreviations: HDP, high-density parasitemia (≥10,000 parasites/μl); SMA, severe malarial anemia (Hb < 6.0 g/dl, with parasitemia of any density) (29); non-SMA, nonsevere malarial anemia (11.0 g/dl > Hb ≥ 6.0 g/dl, with parasitemia of any density); N/A, not available.
b
Statistical significance determined by chi-square analysis.
c
Statistical significance determined by Mann-Whitney U test.