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Histologic sections of lungs from rats resistant to intranasal infection with KIM D27 show multiple foci of active inflammation. Six- to 8-week-old rats (3 per strain) were intranasally infected with 1 × 107 CFU of Y. pestis KIM D27 and were sacrificed on day 14 for histologic evaluation of lungs. (A to E) H&E-stained lung sections from infected Brown Norway (A), ACI (B), Fischer 344 (C), Lewis (D), and Wistar Furth (E) rats. (F) Control lung tissue from an uninfected Brown Norway rat.
